Net Reclassification Index: a Misleading Measure of Prediction Improvement
نویسندگان
چکیده
منابع مشابه
Comparison of Bayesian and Frequentist Methods in Estimating the Net Reclassification and Integrated Discrimination Improvement Indices for Evaluation of Prediction Models: Tehran Lipid and Glucose Study
Introduction: The Frequency-based method is commonly used to estimate the Net Reclassification Improvement (NRI)- and Integrated Discrimination Improvement (IDI) indices. These indices measure the magnitude of the performance of statistical models when a new biomarker is added. This method has poor performance in some cases, especially in small samples. In this study, the performance of two Bay...
متن کاملImprovement of risk prediction by genomic profiling: reclassification measures versus the area under the receiver operating characteristic curve.
Reclassification is observed even when there is no or minimal improvement in the area under the receiver operating characteristic curve (AUC), and it is unclear whether it indicates improved clinical utility. The authors investigated total reclassification, net reclassification improvement, and integrated discrimination improvement for different DeltaAUC using empirical and simulated data. Empi...
متن کاملNet reclassification indices for evaluating risk prediction instruments: a critical review.
Net reclassification indices have recently become popular statistics for measuring the prediction increment of new biomarkers. We review the various types of net reclassification indices and their correct interpretations. We evaluate the advantages and disadvantages of quantifying the prediction increment with these indices. For predefined risk categories, we relate net reclassification indices...
متن کاملCommentary: Reporting standards are needed for evaluations of risk reclassification.
New approaches have been developed in recent years to quantify the improvement in prediction performance gained by adding a novel marker to a set of baseline predictors of risk. The paper by Tzoulaki et al. concerns risk reclassification techniques and focuses specifically on the net reclassification improvement (NRI) index. Their review shows that use of risk reclassification analysis is extre...
متن کاملClinically relevant measures of fit? A note of caution.
Risk reclassification methods have become popular in the medical literature as a means of comparing risk prediction models. In this issue of the Journal, Pencina et al. (Am J Epidemiol. 2012;176(6):492-494) present further results for continuous measures of model discrimination and describe their characteristics in nested models with normally distributed variables. Measures include the change i...
متن کامل